Physics based modeling using the worlds fastest supercomputer Key to understanding the ALS Disease mechanism is figuring out the physical workings of ALS cellular pathology. The initial focus will be on the formation of the aberrant TAR DNA-binding protein 43 (TDP-43) inclusions or clusters that transition into pathological, amyloid-like fibrils. This clustered form of TDP-43 is present in over 95% of ALS patients and will be the initial focus of modeling simulations.
Understanding the ALS Disease mechanism is a vital first step towards a cure for ALS.
The Oakland A's highlighted the ALS CURE Project as the virtual Non-Profit Partner of the game at the Wednesday July 29th game vs the Colorado Rockies. A highly successful and fun silent auction was conducted during and after the game. This was a special game featuring Stephen Piscotty and Sam Hilliard who both have parents who have been afflicted by ALS.
The ALS CURE Project partnership with the Livermore Lab Foundation (LLF) to conduct ALS research at Lawrence Livermore National Laboratory (LLNL) was featured in the LLF 2019 Philanthropic Report. Under this partnership with the LLF, LLNL will be applying world-class data analytics to discover ALS biomarkers and to gain an understanding of the ALS disease mechanism.
Due to the Corona Virus we are postponing the golf tournamet until it is safe for all to attend and support a good cause.
Over 200 people enjoyed the ALS Cure Gala including a dozen Oakland Athletics players including Matt Chapman, Liam Henricks, Gold Glover Matt Olson, Chad Pinder, Stephen Piscotty and their teammates.
A council driven approach leveraging industry expertise to achieve ALS CURE strategic objectives.
Stephen and Mike Piscotty created ALS CURE Project as a promise to Gretchen to work towards elimination of ALS as a scourge on humanity.
The specific purpose of ALS CURE Project is to lead scientific research focused on the identification of Amyotrophic Lateral Sclerosis (ALS) biomarkers and disease mechanism with the ultimate goal of finding a cure for ALS.
ALS CURE Project is a 501(c)(3) public charity registered in the United States, EIN# 84-3289802. Contributions will be tax-deductible. 2808 Longspur Way, Pleasanton, CA 94566 firstname.lastname@example.org
ALS CURE Project raises funds internationally and sponsors research in the US and UK.